As one of the faces of the 1990s, Freddie rose to fame starring in such movies as She's All That, I Know What You Did Last Summer, and the sequel I Still Know What You Did Last Summer. He later starred in the Scooby Doo franchise and Summer Catch opposite Jessica Biel.
In 2005 Freddie created and starred in a sitcom for ABC based on his own life, and aptly named Freddie.
Post-Freddie, Prinze has guest starred on programs like Psych, Boston Legal, and The George Lopez Show.
In 2010 Freddie joined the cast of 24 for its final season as "Agent Cole Ortiz," CTU's New York Director of Operations. His memorable arc found him playing both sides as he navigated a complex relationship with "Dana Walsh" (Katee Sackhoff) while serving in the field alongside Keifer Sutherland's "Jack Bauer" as they fight to protect New York from terrorists.
In 2016 Freddie was the host for USA's First Impressions with Dana Carvey and released his first cookbook Back in the Kitchen in June. Currently, Freddie voices the Jedi character Kanan in the animated series Star Wars Rebels, which airs on Disney XD.
Also an active writer and producer, Freddie lives in Los Angeles with his wife Sarah Michelle Gellar.