Michael Shuler

Biotechnology & Bioengineering Gaden Award

This award was established by John Wiley & Sons, Inc. and the journal Biotechnology & Bioengineering in honor of its founding editor Elmer Gaden, Jr., and recognizes a high-impact paper reflecting exceptional innovation, creativity and originality. This award is presented annually at the National ACS Meeting at a session of the BIOT Division. This year, Professor Shuler is being recognized for his paper “Microfluidic Blood-Brain Barrier Model Provides In Vivo-Like Barrier Properties for Drug Permeability Screening,” by Ying I. Wang, Hasan Erbil Abaci, Michael L. Shuler, Biotechnology & Bioengineering 114(1), 184-194 (2016).

Michael L. Shuler is the Samuel B. Eckert Professor of Engineering in the Meing School of Biomedical Engineering and in the Smith School of Chemical and Biomolecular Engineering at Cornell University, Ithaca, New York. He was the director for a NCI funded Physical Sciences- Oncology Center (Center for the Microenvironment and Metastasis) and Cornell's Nanobiotechnology Center. Shuler received both of his degrees in chemical engineering (BS, University of Notre Dame, 1969 and Ph.D., University of Minnesota, 1973) and has been a faculty member at Cornell University since January 1974. Shuler's research is focused on biomolecular engineering and includes development of “Body- on-a-Chip” or microphysiological system for testing pharmaceuticals and chemicals for toxicity, creation of production systems for useful compounds, such as paclitaxel from plant cell cultures, and constructions of computer models of cells relating physiological function to genomic structure. Shuler's research has helped to lay the foundation for modern biochemical engineering and has led to commercial processes for production of the anticancer agent, Taxol, to tools to produce proteins from recombinant DNA (the “High Five” cell line), to software to support systems biology, such as a model of a minimal bacterial cell, and to devices for drug development (“Body-on-a-Chip”).